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Our achievements

The company's employees are high-level specialists in the field of tissue engineering and molecular biology, annually publish their research in journals cited in the Web of Science and Scopus databases. And they are also the authors of a large number of patents and unique laboratory developments.

Patents

  1. A method for manufacturing prostheses of small diameter blood vessels used for its electrospinning and a device for its implementation

    A.A. Gostev, P.P. Laktionov, G.A. Rasskazov, V.S. Chernonosova, A.O. Stepanova, A.V. Shutov, A.A. Karpenko, A.M. Karaskov, E.A. Pokushalov.
    Patent for invention 2,704,314. Priority dated April 28, 2018, registered on October 28, 2019, published on October 28, 2019 Bull. No. 31

  2. A method for producing a microfiber material that releases drugs.

    A.O. Stepanova, K.A. Kuznetsov, O.A. Novikova, E.A. Pokushalov, A.A. Karpenko, P.P. Laktionov.
    Patent for invention No. (19) RU (11) 2 669 344 (13) C1. Starting date of the patent term: 02.11.2017. Date of registration: 10.10.2018. Published: 10.10.2018 Bull. No. 28

  3. A method for producing a microfiber material that releases drugs

    Stepanova A.O., Kuznetsov K.A., Novikova O.A., Pokushalov E.A., Karpenko A.A., Laktionov P.P.
    2017 No. 2669344

  4. Detergent-free procedure for decellularization of (xenogenic) biological tissues intended for human surgery.

    Laktionov P.P., Chernonosova V.S., Rasskazov G.A., Cherepanova A.V., Karpenko A.A. and that's all.
    Korean patent application N10-2019-0074334, priority dated 06/21/2019.

  5. Biograft for restoration of defects in cartilage tissue of joints and photopolymerizable hydrogel for its use.

    V.S. Chernonosova, T.S. Godovikova, A.O. Stepanova, O.B. Naumenko, V.V. Vlasov, P.P. Laktionov.
    Patent for invention No. RU2593011 C1. Starting date of the patent validity period: 07.16.2015. Date of registration: 27.07.2016.

Publications

  1. Influence of Elongation of Paclitaxel-Eluting Electrospun-Produced Stent Coating on Paclitaxel Release and Transport through the Arterial Wall after Stenting

    Z. Nazarkina, B. Chelobanov, K. Kuznetsov, A. Shutov, I. Romanova, A. Karpenko, P. Laktionov.
    2021, POLYMERS, 13 (7), DOI, Q1

  2. Assessment of electrospun pellethane–based scaffolds for vascular tissue engineering.

    Chernonosova V.S., Gostev A.A., Murashov I.S., Chelobanov B.P., Karpenko A.A., Laktionov P.P.
    2020;19. DOI

  3. Comparative gene expression profiling of human primary endotheliocytes cultivated on polyurethane-based electrospun 3D matrices and natural decellularized vein.

    Chernonosova V.S., Laktionov Petr P., Murashov I.S., Karpenko A.A., Laktionov P.P.
    Biomedical Materials, 2020, 15(4), DOI

  4. In Vivo Stability of Polyurethane-Based Electrospun Vascular Grafts in Terms of Chemistry and Mechanics.

    Gostev A.A, Shundrina I.K., Pastukhov V.I., Shutov A.V., Chernonosova V.S., Karpenko A.A. and Laktionov P.P.
    Polymers, 2020, 12, 845; DOI, Q1

  5. Sirolimus-Eluting Electrospun-Produced Matrices as Coatings for Vascular Stents: Dependence of Drug Release on Matrix Structure and Composition of the External Environment.

    Nazarkina Zh.K., Chelobanov B.P., Chernonosova V.S., Romanova I.V., Karpenko A.A. and Laktionov P.P.
    Materials 2020, 13(12), 2692;DOI

  6. Vascular stents coated with electrospun drug-eluting material: functioning in rabbit iliac artery.

    K.A. Kuznetsov, I.S. Murashov, V.S. Chernonosova, B.P. Chelobanov, А.O. Stepanova, D. S. Sergeevichev, A.A. Karpenko, P.P. Laktionov
    Polymers 2020. DOI.

  7. Mechanisms Underlying Atheroma Induction: The Roles of Mechanotransduction, Vascular Wall Cells, and Blood Cells.

    Novikova O.A., Laktionov P.P., Karpenko A.A.
    2018, Ann Vasc Surg. Volume 53, Pages 224-233. DOI

  8. Isolation, culturing and gene expression profiling of inner mass cells from stable and vulnerable carotid atherosclerotic plaques

    Novikova O.A., Nazarkina Z.K., Cherepanova A.V., Laktionov P.P., Chelobanov B.P., Murashov I.S., Deev R.V., Pokushalov E.A., Karpenko A.A., Laktionov P.P.
    PLoS One. 2019 Jun 26;14(6):e0218892. DOIPMID: 31242269

  9. Isolation And Culture Of Carotid Atherosclerotic Plaque Inner Mass Cells

    O. Novikova, A. Cherepanova, Z. Nazarkina, P. Laktionov, P. Laktionov.
    2019, Atherosclerosis, Volume 287, Pages e269-e270, DOI, Q1

  10. General Study and Gene Expression Profiling of Endotheliocytes Cultivated on Electrospun Materials.

    Stepanova AO, Laktionov PP, Cherepanova AV, Chernonosova VS, Shevelev GY, Zaporozhchenko IA, Karaskov AM, Laktionov PP
    General Study and Gene Expression Profiling of Endotheliocytes Cultivated on Electrospun Materials. 2019, Materials (Basel). 12(24), 4082.DOI.

  11. Diclofenac release form polycaprolactone 3D matrices produced by electrospinning: influence of fiber structure and composition of the surrounding medium.

    Kuznetsov K.A., Stepanova A.O., Kuznetsov N.A., Сhernonosova V.S., Kharkova M.V., Romanova I.V., Karpenko A.A., Laktionov P.P.
    2019, International Journal of Polymeric Materials and Polymeric Biomaterials 68(1-3), p. 27-33. DOI

  12. Mechanical Properties and Biological Behavior of 3D Matrices Produced by Electrospinning from Protein-Enriched Polyurethane

    Chernonosova VS, Gostev AA, Gao Y, Chesalov YA, Shutov AV, Pokushalov EA, Karpenko AA, Laktionov PP.
    Biomed Res Int. 2018, Biomed Res Int. Volume 2018 |Article ID 1380606, DOI .

  13. Polyurethanes in cardiovascular prosthetics.

    A. A. Gostev, A. A. Karpenko, P. P. Laktionov
    Polymer Bulletin. September 2018, Volume 75, Issue 9, pp 4311–4325 DOI

  14. A.V. Cherepanova, D. Akisheva, I.V. Popova, B.P. Chelobanov, Yu.A. Chesalov, T.S. Godovikova, A.A. Karpenko, P.P. Laktionov

    A.V. Cherepanova, D. Akisheva, I.V. Popova, B.P. Chelobanov, Yu.A. Chesalov, T.S. Godovikova, A.A. Karpenko, P.P. Laktionov
    2019, Russian Journal of Bioorganic Chemistry 45(6):793-802, DOI1

  15. Study of hemocompatibility and endothelial cell interaction of tecoflex-based electrospun vascular grafts.

    Chernonosova, V.S., Gostev, A.A., Chesalov, Y.A., Karpenko A.A., Karaskov, A.M., Laktionov, P.P.
    International Journal of Polymeric Materials and Polymeric Biomaterials, 68(1-3), p. 34-43. DOI

  16. Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment.

    K.A. Kuznetsov, A.O. Stepanova, R.I. Kvon, T.E. L. Douglas, N.A. Kuznetsov, V.S. Chernonosova, I.A. Zaporozhchenko, M.V. Kharkova, I.V. Romanova, A. A. Karpenko, P.P. Laktionov.
    2018, Materials, 11(11), 2176; DOI

  17. The study of the surface layer of 3D-matrices for tissue engineering.

    Chernonosova V.S , Kvon R.I., Kiseleva E.V., Stepanova A.O., Laktionov P.P.
    Biochemistry (Moscow) Supplement series B: Biomedical Chemistry. 2017, vol. 11, № 2, pp.139-145, DOI

  18. Human serum albumin in electrospun PCL fibers: structure, release, and exposure on fiber surface

    V. S. Chernonosova, R. I. Kvon, A. O. Stepanova, Y. V. Larichev, A. A. Karpenko, B. P. Chelobanov, E. V. Kiseleva, P. P. Laktionov.
    2017, Polymers for Advanced Technologies, Volume 28, Issue 7, Pages 819–827, DOI , Q1